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The Science Behind Photobiomodulation: Can Light Really Make Hair Grow?

Around the world, 40% of men display visible hair thinning by age 35. The same is true for women, but by age 40. This can be caused from a wide range of factors: anything from poor diet to a natural hair loss caused by advancing age. For the millions of people facing thinning hair, solutions may feel elusive and impossible. However, recent technology has emerged that show promise at combatting this problem by encouraging regrowth using nothing but red and near-infrared light. Known as low-level laser therapy, LLLT has made significant progress in the last 2 decades, rapidly moving from a laboratory experiment to a consumer-grade product. But does it actually work? The Premise The premise of LLLT is based on a well known phenomenon called photobiomodulation. The science is simple. Inside the mitochondrial membrane of hair follicles, we can find a specific type of enzyme called cytochrome c oxidase. Also known as Complex IV, it accepts electrons from cytochrome c and reduces mol...

Why do we have 5 fingers and toes?

Why do we have 5 fingers and toes




Have you ever wondered why humans have five fingers and toes on each hand and foot? It's a question that has puzzled scientists and researchers for years. While there are many theories about why we have five digits, the most widely accepted explanation is that it's simply the result of evolution.

 Evolutionary History

The common ancestor of all mammals, birds, reptiles, and amphibians had five digits, and we have stuck with that number. Many groups have lost digits, but five is still the basic number. For example, a horse has a single toe on each foot, but if you look at an early horse embryo, its limb buds have five little stripes of Sox9, just like ours. Some might say that we never need more than five fingers and toes, but that's not entirely true. Some people are born with more than five digits, a condition known as polydactyly. Ernest Hemingway used to own a six-toed cat, whose descendants still live in the writer’s Florida home. And the first tetrapods (four-legged animals) to invade the land had anywhere up to eight toes per foot.

 Advantages of Five Digits

So why did evolution settle on five digits as the optimal number? One theory is that five fingers and toes provide the best balance between dexterity and stability. With five digits, we can easily grasp and manipulate objects, while still maintaining a stable base for walking and running. This balance between dexterity and stability may have been crucial for early humans as they evolved to use tools and walk upright.

Another theory is that five digits are simply the result of a genetic "default setting". The genes that control the development of fingers and toes are part of a complex system known as the Turing system. This system is responsible for creating the patterns of digits that we see in different animals. However, the Turing system is highly flexible, and small changes in the parameters can result in different numbers of digits. So why has evolution set these parameters so they almost always make five? It’s clearly possible to make more, but five seems to be the most efficient number for our needs.

 Other Animals

Humans are not the only animals with five digits. Many other primates, such as monkeys and apes, also have five fingers and toes. However, some animals have more or fewer digits. For example, dogs and cats have four toes on their front paws and five on their back paws. Birds have three toes, and some dinosaurs had as few as two. The number of digits an animal has depends on a variety of factors, including its evolutionary history, its environment, and the demands of its lifestyle.

In conclusion, the reason why humans have five fingers and toes is a result of evolution. While there are many theories about why five digits are optimal, the most widely accepted explanation is that it's simply the result of a genetic "default setting" that has been optimized over millions of years of evolution. While some animals have more or fewer digits, five seems to be the most efficient number for our needs. So the next time you look at your hands and feet, remember that they are the result of millions of years of evolution, and that five fingers and toes are the perfect balance between dexterity and stability.

Citations:
[1] https://www.nationalgeographic.com/science/article/how-did-you-get-five-fingers
[2] https://www.reddit.com/r/evolution/comments/nnc4td/is_there_any_good_explanation_why_we_evolved_to/
[3] https://www.thedoseum.org/Do-it-at-home/posts/5-fingers-5-toes
[4] https://askdruniverse.wsu.edu/2018/12/14/five-fingers-toes/
[5] https://www.newscientist.com/lastword/mg25233662-300-why-do-we-have-five-digits-on-each-hand-and-not-some-other-number/
[6] https://blogs.ubc.ca/communicatingchemistry2017w110/2017/10/31/why-people-have-5-fingers/

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